Record Information
public_id FDB015350
Chemical Information
name Uric acid
description Occurs as phosphate in yeast and meat products For example, some researchers propose that hyperuricemia-induced oxidative stress is a cause of metabolic syndrome. On the other hand, plasma uric acid levels correlate with longevity in primates and other mammals. This is presumably a function of urate's antioxidant properties.; Uric acid (or urate) is an organic compound of carbon, nitrogen, oxygen and hydrogen with the formula C5H4N4O3.; Uric acid is a heterocyclic purine derivative that is the final oxidation product of purine metabolism. It is produced by the enzyme xanthine oxidase, which oxidizes oxypurines such as xanthine into uric acid. In most mammals, except humans and higher primates, the enzyme uricase further oxidizes uric acid to allantoin. Uric acid is also the end product of nitrogen metabolism in birds and reptiles. In such species, it is excreted in feces as a dry mass. Humans produce only small quantities of uric acid with excess accumulation leading to a type of arthritis known as gout. The loss of uricase in higher primates parallels the similar loss of the ability to synthesize ascorbic acid vitamin C. This may be because in higher primates uric acid partially replaces ascorbic acid.
cas_number 69-93-2
Properties
created_at 2010-04-08 22:11:47
updated_at 2011-10-30 14:31:25
moldb_smiles O=C1NC2=C(N1)C(=O)NC(=O)N2
moldb_formula C5H4N4O3
moldb_average_mass 168.1103
moldb_inchi InChI=1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)
moldb_mono_mass 168.028340014
moldb_inchikey InChIKey=LEHOTFFKMJEONL-UHFFFAOYSA-N
moldb_iupac 2,3,6,7,8,9-hexahydro-1H-purine-2,6,8-trione
Structure Thumb
Synonyms
Synonym Source
1H-Purine-2, 6,8-triol biospider
1H-Purine-2,6,8(3H)-trione, 7,9-dihydro- biospider
1H-Purine-2,6,8(3H)-trione, 7,9-dihydro- (9CI) biospider
1H-Purine-2,6,8-triol biospider
1H-Purine-2,6,8-triol 2,6,8-Trihydroxypurine biospider
2,6, 8-Trioxypurine biospider
2,6,8-Trihydroxypurine db_source
2,6,8-Trioxopurine biospider
2,6,8-Trioxypurine biospider
2,6-dihydroxy-7,9-dihydro-8H-purin-8-one biospider
6,8-Dioxo-6,7,8,9-tetrahydro-1H-purin-2-olate biospider
7,9-Dihydro-1H-purine-2,6,8(3H)-trione biospider
7,9-dihydro-3H-purine-2,6,8-trione biospider
7H-purine-2,6,8-triol biospider
8-Hydroxyxanthine biospider
9H-purine-2,6,8-triol biospider
Acid urate, ammonium biospider
Acid urate, sodium biospider
Acid, uric biospider
Acidum Uricum-Injeel Forte Liq (D6-D200) biospider
Ammonium acid urate biospider
Lithate biospider
Lithic acid biospider
Monohydrate, monosodium urate biospider
Monohydrate, sodium urate biospider
Monosodium urate biospider
Monosodium urate monohydrate biospider
Potassium urate biospider
Purine-2,6,8(1H,3H,9H)-trione biospider
purine-2,6,8-(1H,3H,9H)-trione biospider
Purine-2,6,8-triol biospider
Purine-3,6,8(1H,3H,9H)-trione biospider
Sodium acid urate biospider
Sodium acid urate monohydrate biospider
Sodium urate biospider
Sodium urate monohydrate biospider
Trioxopurine biospider
Urate biospider
Urate monohydrate, monosodium biospider
Urate monohydrate, sodium biospider
Urate, ammonium acid biospider
Urate, monosodium biospider
Urate, potassium biospider
Urate, sodium biospider
Urate, sodium acid biospider
URC biospider
Uric acid (8CI) biospider
Uric oxide biospider
Uricum acidum biospider
Uricum Acidum 3-30ch biospider
2,6,8(1H,3H,9H)-Purinetrione db_source
7,9-Dihydro-1H-purine-2,6,8(3H)-trione, 9CI db_source